Syracuse Police say two men, 17 and 20 years old, were standing on the corner of East Colvin Street and Midland Avenue at about 4 p.m. when they were shot.
Police say the suspect - who was in a gray sedan - was last seen driving southbound on Midland Avenue.
The victims were taken to Upstate University Hospital with non-life threatening injuries.
Police say the drive-by shooting is an ongoing investigating and urge anyone with information to call them at (315) 442-5222.
All calls will remain confidential.
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