The Orange defeated Boston College by a score of 11-9 at the Carrier Dome to advance on Saturday.
SU was led by senior Katie Webster, who went to Christian Brothers Academy in Syracuse.
Webster scored three goals during a 9-2 scoring run by the Orange.
The win is also the Orange's 20th of the season.
It is the first time that has happened in program history.
SU's next opponent is Virginia. They will play each other on Friday, May 23 in Maryland.
Syracuse and Virginia played earlier this season on February 23. SU won 18-14.
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